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THE JOURNEY THROUGH TIME

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Events

Moments that changed communities, movements, institutions and the nation.

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MY'STORY

The MOVE Fire

This is a personal recollection on the Move fire on May 13, 1985 Philadelphia police fired thousands of rounds at the MOVE house, city officials approved dropping an explosive device on the roof, the resulting fire was allowed to burn, 11 people—including five children—died, and 61 homes were destroyed. Philadelphia City Council later called it a “brutal attack carried out by the City of Philadelphia on its own citizens” and acknowledged that no individual faced criminal consequences for the bombing. One timeline correction worth preserving for the BHP record: the major previous MOVE-police confrontation was August 8, 1978, about seven years before the bombing, not a year or two earlier. Officer James Ramp was killed, other police and firefighters were wounded, nine MOVE members were later convicted, and television cameras recorded police beating Delbert Africa during his arrest. The 1985 MOVE Commission later specifically criticized city planners for failing to adequately use lessons from that 1978 confrontation. And that actually strengthens the point you’re making: 1985 did not happen without precedent or institutional memory. There had already been a deadly confrontation with MOVE, years of conflict, negotiations and police involvement before Osage Avenue.

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BLACK FACTS
The Truths They Never Taught You...

The Violence That Helped Spark the NAACP

In August 1908, a white mob attacked Springfield, Illinois’s Black community, destroying homes and businesses and lynching two Black men. National outrage over the violence helped spur the movement that created the NAACP the following year.

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BHP gathered finds from its connected research sources. Showing the 4 strongest Black History matches.
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Wikipedia

Intermediate-term memory

Intermediate-term memory (ITM) is a stage of memory distinct from sensory memory, working memory/short-term memory, and long-term memory.[1][2][3] While sensory memory persists for several milliseconds, working memory persists for up to thirty seconds, and long-term memory persists from thirty minutes to the end of an individual's life, intermediate-term memory persists for about two to three hours.[4] This overlap in the durations of these memory processes indicates that they occur simultaneously, rather than sequentially. Indeed, intermediate-term facilitation can be produced in the absence of long-term facilitation.[5] However, the boundaries between these forms of memory are not clear-cut, and they can vary depending on the task.[6] Intermediate-term memory is thought to be supported by the parahippocampal cortex.[7]

In 1993, Rosenzweig and colleagues demonstrated that, in chicks conditioned with an aversive stimulus, percent avoidance of the stimulus (and, by implication, memory of the aversive nature of the stimulus) reached relative minima at one minute, fifteen minutes, and sixty minutes.[8] These dips were theorized to correspond to the time points in which the chicks switched from working memory to intermediate-term memory, from intermediate-term memory to the early phase of long-term memory, and from the early phase of long-term memory to the late phase of long-term memory, respectively—thus demonstrating the presence of a form of memory that exists between working memory and long-term memory, which they referred to as "intermediate-term memory".

Though the idea of intermediate-term memory has existed since the 1990s, Sutton et al. introduced a novel theory for the neural correlates underlying intermediate-term memory in Aplysia in 2001, where they described it as the primary behavioral manifestation of intermediate-term facilitation.[9]

Characteristics

[edit]

In 2001, Sutton and colleagues proposed that intermediate-term memory possesses the following 3 characteristics:

Mechanism

[edit]

Induction

[edit]

Because intermediate-term memory does not involve transcription, it likely involves the translation of mRNA transcripts already present in neurons.[4][12][13][14][15][16][17][18][19][20][21][22]

Comparison with short-term/working memory

[edit]

Unlike short-term memory and working memory, intermediate-term memory requires changes in translation to occur in order to function.

Comparison with long-term memory

[edit]

While ITM requires only changes in translation, induction of long-term memory requires changes in transcription as well.[23] The change from short-term memory to long-term memory is thought to dependent on CREB, which regulates transcription, but because ITM does not involve a change in transcription, it is thought to be independent of CREB activity.[4] According to the definition of ITM proposed by Sutton et al. in 2001, it disappears completely before long-term memory is induced.[9]

References

[edit]
  1. ^ Kamiński J (May 2017). "Intermediate-Term Memory as a Bridge between Working and Long-Term Memory". The Journal of Neuroscience. 37 (20): 5045–5047. doi:10.1523/JNEUROSCI.0604-17.2017. PMC 6596466. PMID 28515306.
  2. ^ Grimes MT, Smith M, Li X, Darby-King A, Harley CW, McLean JH (March 2011). "Mammalian intermediate-term memory: new findings in neonate rat". Neurobiology of Learning and Memory. 95 (3): 385–91. doi:10.1016/j.nlm.2011.01.012. PMID 21296674. S2CID 29925493.
  3. ^ Sutton MA, Carew TJ (August 2002). "Behavioral, cellular, and molecular analysis of memory in aplysia I: intermediate-term memory" (PDF). Integrative and Comparative Biology. 42 (4): 725–35. doi:10.1093/icb/42.4.725. PMID 21708769. S2CID 18292115.
  4. ^ a b c Lukowiak K, Adatia N, Krygier D, Syed N (2000). "Operant conditioning in Lymnaea: evidence for intermediate- and long-term memory". Learning & Memory. 7 (3): 140–50. doi:10.1101/lm.7.3.140. PMC 311329. PMID 10837503.
  5. ^ Mauelshagen J, Sherff CM, Carew TJ (1998). "Differential induction of long-term synaptic facilitation by spaced and massed applications of serotonin at sensory neuron synapses of Aplysia californica". Learning & Memory. 5 (3): 246–56. doi:10.1101/lm.5.3.246. PMC 313806. PMID 10454368.
  6. ^ Kesner RP, Martinez Jr JL, eds. (2007). Neurobiology of Learning and Memory (2nd ed.). Nikki Levy, Academic Press. p. 284. ISBN 978-0-12-372540-0.
  7. ^ Eichenbaum H, Otto T, Cohen NJ (2010). "Two functional components of the hippocampal memory system". Behavioral and Brain Sciences. 17 (3): 449–472. doi:10.1017/S0140525X00035391. S2CID 144756396.
  8. ^ Rosenzweig MR, Bennett EL, Colombo PJ, Lee DW, Serrano PA (November 1993). "Short-term, intermediate-term, and long-term memories". Behavioural Brain Research. 57 (2): 193–8. doi:10.1016/0166-4328(93)90135-D. PMID 8117424. S2CID 4016577.
  9. ^ a b c d e Sutton MA, Masters SE, Bagnall MW, Carew TJ (July 2001). "Molecular mechanisms underlying a unique intermediate phase of memory in aplysia". Neuron. 31 (1): 143–54. doi:10.1016/S0896-6273(01)00342-7. PMID 11498057. S2CID 14711555.
  10. ^ Parvez K, Stewart O, Sangha S, Lukowiak K (April 2005). "Boosting intermediate-term into long-term memory". The Journal of Experimental Biology. 208 (Pt 8): 1525–36. Bibcode:2005JExpB.208.1525P. doi:10.1242/jeb.01545. PMID 15802676.
  11. ^ Sutton MA, Bagnall MW, Sharma SK, Shobe J, Carew TJ (April 2004). "Intermediate-term memory for site-specific sensitization in aplysia is maintained by persistent activation of protein kinase C". The Journal of Neuroscience. 24 (14): 3600–9. doi:10.1523/JNEUROSCI.1134-03.2004. PMC 6729755. PMID 15071108.
  12. ^ Stough S, Shobe JL, Carew TJ (December 2006). "Intermediate-term processes in memory formation". Current Opinion in Neurobiology. 16 (6): 672–8. doi:10.1016/j.conb.2006.10.009. PMID 17097872. S2CID 23152510.
  13. ^ Sutton MA, Ide J, Masters SE, Carew TJ (2002). "Interaction between amount and pattern of training in the induction of intermediate- and long-term memory for sensitization in aplysia". Learning & Memory. 9 (1): 29–40. doi:10.1101/lm.44802. PMC 155928. PMID 11917004.
  14. ^ Sharma SK, Bagnall MW, Sutton MA, Carew TJ (April 2003). "Inhibition of calcineurin facilitates the induction of memory for sensitization in Aplysia: requirement of mitogen-activated protein kinase". Proceedings of the National Academy of Sciences of the United States of America. 100 (8): 4861–6. Bibcode:2003PNAS..100.4861S. doi:10.1073/pnas.0830994100. PMC 153646. PMID 12672952.
  15. ^ Sutton MA, Schuman EM (October 2006). "Dendritic protein synthesis, synaptic plasticity, and memory". Cell. 127 (1): 49–58. doi:10.1016/j.cell.2006.09.014. PMID 17018276. S2CID 17065447.
  16. ^ Zhao Y, Leal K, Abi-Farah C, Martin KC, Sossin WS, Klein M (August 2006). "Isoform specificity of PKC translocation in living Aplysia sensory neurons and a role for Ca2+-dependent PKC APL I in the induction of intermediate-term facilitation". The Journal of Neuroscience. 26 (34): 8847–56. doi:10.1523/JNEUROSCI.1919-06.2006. PMC 6674363. PMID 16928874.
  17. ^ Michel M, Green CL, Gardner JS, Organ CL, Lyons LC (March 2012). "Massed training-induced intermediate-term operant memory in aplysia requires protein synthesis and multiple persistent kinase cascades". The Journal of Neuroscience. 32 (13): 4581–91. doi:10.1523/JNEUROSCI.6264-11.2012. PMC 3329157. PMID 22457504.
  18. ^ Antonov I, Kandel ER, Hawkins RD (April 2010). "Presynaptic and postsynaptic mechanisms of synaptic plasticity and metaplasticity during intermediate-term memory formation in Aplysia". The Journal of Neuroscience. 30 (16): 5781–91. doi:10.1523/JNEUROSCI.4947-09.2010. PMC 6632334. PMID 20410130.
  19. ^ Michel M, Gardner JS, Green CL, Organ CL, Lyons LC (March 2013). "Protein phosphatase-dependent circadian regulation of intermediate-term associative memory". The Journal of Neuroscience. 33 (10): 4605–13. doi:10.1523/JNEUROSCI.4534-12.2013. PMC 3723391. PMID 23467376.
  20. ^ Sutton MA, Carew TJ (April 2000). "Parallel molecular pathways mediate expression of distinct forms of intermediate-term facilitation at tail sensory-motor synapses in Aplysia". Neuron. 26 (1): 219–31. doi:10.1016/S0896-6273(00)81152-6. PMID 10798406. S2CID 17622485.
  21. ^ Parvez K, Moisseev V, Lukowiak K (July 2006). "A context-specific single contingent-reinforcing stimulus boosts intermediate-term memory into long-term memory". The European Journal of Neuroscience. 24 (2): 606–16. doi:10.1111/j.1460-9568.2006.04952.x. PMID 16903862. S2CID 21113626.
  22. ^ Zhang L, Ouyang M, Ganellin CR, Thomas SA (March 2013). "The slow afterhyperpolarization: a target of β1-adrenergic signaling in hippocampus-dependent memory retrieval". The Journal of Neuroscience. 33 (11): 5006–16. doi:10.1523/JNEUROSCI.3834-12.2013. PMC 3632069. PMID 23486971.
  23. ^ Braun MH, Lukowiak K (September 2011). "Intermediate and long-term memory are different at the neuronal level in Lymnaea stagnalis (L.)". Neurobiology of Learning and Memory. 96 (2): 403–16. doi:10.1016/j.nlm.2011.06.016. PMID 21757019. S2CID 20487786.

Source: Wikipedia. Article content is retrieved live through the MediaWiki API.

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Wikipedia

Intermediate-term memory

Intermediate-term memory (ITM) is a stage of memory distinct from sensory memory, working memory/short-term memory, and long-term memory. While sensory memory persists for several milliseconds, working memory persists for up to thirty seconds, and long-term memory persists from thirty minutes to the end of an individual's life, intermediate-term memory persists for about two to three hours. This overlap in the durations of these memory processes indicates that they occur simultaneously, rather than sequentially. Indeed, intermediate-term facilitation can be produced in the absence of long-term facilitation. However, the boundaries between these forms of memory are not clear-cut, and they can vary depending on the task. Intermediate-term memory is thought to be supported by the parahippocampal cortex. In 1993, Rosenzweig and colleagues demonstrated that, in chicks conditioned with an aversive stimulus, percent avoidance of the stimulus (and, by implication, memory of the aversive nature of the stimulus) reached relative minima at one minute, fifteen minutes, and sixty minutes. These dips were theorized to correspond to the time points in which the chicks switched from working memory to intermediate-term memory, from intermediate-term memory to the early phase of long-term memory, and from the early phase of long-term memory to the late phase of long-term memory, respectively—thus demonstrating the presence of a form of memory that exists between working memory and long-term memory, which they referred to as "intermediate-term memory". Though the idea of intermediate-term memory has existed since the 1990s, Sutton et al. introduced a novel theory for the neural correlates underlying intermediate-term memory in Aplysia in 2001, where they described it as the primary behavioral manifestation of intermediate-term facilitation.

MORE →
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Wikipedia

Long-term memory

Long-term memory (LTM) is the stage of the Atkinson–Shiffrin memory model in which informative knowledge is held indefinitely. It is defined in contrast to sensory memory, the initial stage, and short-term or working memory, the second stage, which persists for about 18 to 30 seconds. LTM is grouped into two categories known as explicit memory (declarative memory) and implicit memory (non-declarative memory). Explicit memory is broken down into episodic and semantic memory, while implicit memory includes procedural memory and emotional conditioning.

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Wikipedia

Short-term memory

Short-term memory (or "primary" or "active memory") is the capacity for holding a small amount of information in an active, readily available state for a short interval. For example, short-term memory holds a phone number that has just been recited. The duration of short-term memory (absent rehearsal or active maintenance) is estimated to be on the order of seconds. The commonly cited capacity of 7 items, found in Miller's law, has been superseded by 3-5 items. In contrast, long-term memory holds information indefinitely. Short-term memory is not the same as working memory, which refers to structures and processes used for temporarily storing and manipulating information.

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Wikipedia

Memory

Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. It is the retention of information over time for the purpose of influencing future action. If past events could not be remembered, it would be impossible for language, relationships, or personal identity to develop. Memory loss is usually described as forgetfulness or a disorder such as amnesia. Memory is often understood as an information processing system with explicit and implicit functioning that is made up of a sensory processor, short-term (or working) memory, and long-term memory. This can be related to the neuron. The sensory processor allows information from the outside world to be sensed in the form of chemical and physical stimuli and attended to various levels of focus and intent. Working memory serves as an encoding and retrieval processor. Information in the form of stimuli is encoded in accordance with explicit or implicit functions by the working memory processor. The working memory also retrieves information from previously stored material. Finally, the function of long-term memory is to store information through various categorical models or systems. Declarative, or explicit memory, is the conscious storage and recollection of data. Under declarative memory resides semantic and episodic memory. Semantic memory refers to memory that is encoded with specific meaning. Meanwhile, episodic memory refers to information that is encoded along a spatial and temporal plane. Declarative memory is usually the primary process thought of when referencing memory. Non-declarative, or implicit, memory is the unconscious storage and recollection of information. An example of a non-declarative process would be the unconscious learning or retrieval of information by way of procedural memory, or a priming phenomenon. Priming is the process of subliminally arousing specific responses from memory and shows that not all memory is consciously activated, whereas procedural memory is the slow and gradual learning of skills that often occurs without conscious attention to learning. Memory is not a perfect processor and is affected by many factors. The ways by which information is encoded, stored, and retrieved can all be corrupted. Pain, for example, has been identified as a physical condition that impairs memory, and has been noted in animal models as well as chronic pain patients. The amount of attention given new stimuli can diminish the amount of information that becomes encoded for storage. Also, the storage process can become corrupted by physical damage to areas of the brain that are associated with memory storage, such as the hippocampus. Finally, the retrieval of information from long-term memory can be disrupted because of decay within long-term memory. Normal functioning, decay over time, and brain damage all affect the accuracy and capacity of the memory.

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TOPIC OF THE DAY

Greenwood / Black Wall Street

Before the 1921 destruction of Tulsa’s Greenwood District, Black residents had created a remarkable center of business and community life. The district included stores, professional offices, entertainment venues and homes owned by Black citizens. Understanding Greenwood means learning what was built—not only what was burned.

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TRIVIA QUESTION OF THE DAY

Who was the first African-American woman millionaire in the United States?

Madam C.J. Walker