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THE JOURNEY THROUGH TIME

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Events

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MY'STORY

The MOVE Fire

This is a personal recollection on the Move fire on May 13, 1985 Philadelphia police fired thousands of rounds at the MOVE house, city officials approved dropping an explosive device on the roof, the resulting fire was allowed to burn, 11 people—including five children—died, and 61 homes were destroyed. Philadelphia City Council later called it a “brutal attack carried out by the City of Philadelphia on its own citizens” and acknowledged that no individual faced criminal consequences for the bombing. One timeline correction worth preserving for the BHP record: the major previous MOVE-police confrontation was August 8, 1978, about seven years before the bombing, not a year or two earlier. Officer James Ramp was killed, other police and firefighters were wounded, nine MOVE members were later convicted, and television cameras recorded police beating Delbert Africa during his arrest. The 1985 MOVE Commission later specifically criticized city planners for failing to adequately use lessons from that 1978 confrontation. And that actually strengthens the point you’re making: 1985 did not happen without precedent or institutional memory. There had already been a deadly confrontation with MOVE, years of conflict, negotiations and police involvement before Osage Avenue.

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BLACK FACTS
The Truths They Never Taught You...

The Violence That Helped Spark the NAACP

In August 1908, a white mob attacked Springfield, Illinois’s Black community, destroying homes and businesses and lynching two Black men. National outrage over the violence helped spur the movement that created the NAACP the following year.

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Wikipedia

LCOR

LCOR
Identifiers
AliasesLCOR, MLR2, ligand dependent nuclear receptor corepressor, C10orf12
External IDsOMIM: 607698; MGI: 2443930; GeneCards: LCOR
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001170765
NM_001170766
NM_001346516
NM_015652
NM_032440

NM_172154
NM_001370767

RefSeq (protein)

NP_001164236
NP_001164237
NP_001333445
NP_115816

NP_742166
NP_001357696

Location (UCSC)Chr 10: 96.83 – 97 MbChr 19: 41.47 – 41.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ligand-dependent corepressor is a protein that in humans is encoded by the LCOR gene.[5][6][7]

Function

[edit]

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box.[7]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196233 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025019 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Fernandes I, Bastien Y, Wai T, Nygard K, Lin R, Cormier O, Lee HS, Eng F, Bertos NR, Pelletier N, Mader S, Han VK, Yang XJ, White JH (Jan 2003). "Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms". Mol Cell. 11 (1): 139–50. doi:10.1016/S1097-2765(03)00014-5. PMID 12535528.
  6. ^ White JH, Fernandes I, Mader S, Yang XJ (Jun 2004). "Corepressor recruitment by agonist-bound nuclear receptors". Vitam Horm. Vitamins & Hormones. 68: 123–43. doi:10.1016/S0083-6729(04)68004-6. ISBN 978-0-12-709868-5. PMID 15193453.{{cite journal}}: CS1 maint: periodical has ISBN (link)
  7. ^ a b "Entrez Gene: LCOR ligand dependent nuclear receptor corepressor".

Further reading

[edit]
[edit]
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Ligand-dependent corepressor



Source: Wikipedia. Article content is retrieved live through the MediaWiki API.

Wikipedia

LCOR

Ligand-dependent corepressor is a protein that in humans is encoded by the LCOR gene.

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Wikipedia

John F. Kennedy International Airport

John F. Kennedy International Airport (IATA: JFK, ICAO: KJFK, FAA LID: JFK) is the primary international airport serving the New York metropolitan area. It is located on the southwestern shore of Long Island, in Queens, New York City, bordering Jamaica Bay. It is the busiest of the three airports in the New York airport system, the sixth-busiest airport in the United States. The airport, which covers 5,200 acres (2,104 ha), is the largest in the New York metropolitan area. Nearly 100 airlines operate from JFK Airport, with nonstop or direct flights to destinations on all six permanently inhabited continents. JFK Airport is located in the Jamaica neighborhood of Queens, 16 miles (26 km) southeast of Midtown Manhattan. The airport features five passenger terminals and four runways. It is primarily accessible by car, bus, shuttle, or other vehicular transit via the JFK Expressway or Interstate 678 (Van Wyck Expressway), or by train. JFK is a hub for American Airlines and Delta Air Lines as well as the primary operating base for JetBlue. The airport is also a former hub for Braniff, Eastern, Flying Tigers, National, Northeast, Northwest, Pan Am, Seaboard World, Tower Air, and TWA. The facility opened in 1948 as New York International Airport and was commonly known as Idlewild Airport. Following the assassination of John F. Kennedy in 1963, the airport was renamed John F. Kennedy International Airport in tribute to 35th president of the United States John F. Kennedy.

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Wikipedia

King Street–Old Town station

King Street–Old Town station (also known by its former name, King Street) is a Washington Metro station in Alexandria, Virginia, United States. The station opened on December 17, 1983, and is operated by the Washington Metropolitan Area Transit Authority (WMATA). Providing service for both the Blue and Yellow Lines, this is the southernmost transfer station for the two lines, as they diverge just south of the station. King Street was originally served only by the Yellow Line, until the Blue Line was extended from National Airport to Van Dorn Street in 1991. The station is located at King Street and Commonwealth Avenue. Entrances to the station are located on King Street and on the Diagonal Road side of the station. The station has an elevated island platform over King Street west of Diagonal Road. Two fare control areas on either side of King Street provide escalator and elevator access to the platform.

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Wikipedia

Hoboken Terminal

Hoboken Terminal is a commuter-oriented intermodal passenger station in Hoboken, Hudson County, New Jersey. One of the New York metropolitan area's major transportation hubs, it is served by eight NJ Transit (NJT) commuter rail lines, an NJ Transit event shuttle to Meadowlands Sports Complex, one Metro-North Railroad line, various NJT buses and private bus lines, the Hudson–Bergen Light Rail, the Port Authority Trans-Hudson (PATH) rapid transit system, and NY Waterway-operated ferries. More than 50,000 people use the terminal daily, making it the tenth-busiest railroad station in the United States and the sixth-busiest in the New York area. It is also the second-busiest railroad station in New Jersey, behind only Newark Penn Station, and its third-busiest transportation facility, after Newark Liberty International Airport and Newark Penn Station. The rail and ferry terminal buildings were constructed in 1907 by the Delaware, Lackawanna and Western Railroad, a former Class 1 railroad. In 1930, Thomas Edison was at the controls for the first departure of a regular-service electric multiple-unit train from Hoboken Terminal to Montclair. In 1973, the terminal building was added to the New Jersey Register of Historic Places and the National Register of Historic Places. Hoboken Terminal is considered a milestone in American transportation development, initially combining rail, ferry, subway, streetcar, and pedestrian services. Later, bus and light-rail services were added to the terminals. Another feature of the terminal's design is the terminal's 225-foot (69 m) clock tower. The tower was replaced by a radio tower that stood for more than half a century, until being removed in June 2006, when it was replaced with a new clock tower modeled after the original.

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TOPIC OF THE DAY

Greenwood / Black Wall Street

Before the 1921 destruction of Tulsa’s Greenwood District, Black residents had created a remarkable center of business and community life. The district included stores, professional offices, entertainment venues and homes owned by Black citizens. Understanding Greenwood means learning what was built—not only what was burned.

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TRIVIA QUESTION OF THE DAY

Which Black woman became the first elected to the United States Congress?

Shirley Chisholm, elected in 1968.