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Explore the people, places, events, achievements, struggles and stories that shaped our journey.
Movements, leaders, victories and the continuing fight for equality.
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Pioneers, champions, Negro Leagues, records, activism and excellence.
Meet the people whose lives, choices and achievements shaped the journey.
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Mansa Musa was the ruler of the Mali Empire in West Africa. Details recorded here should be sourced; unknown information is left blank.
MORE →Reflects the personal views, recollections, and perspective of the author, Mike Davis.
This is a personal recollection on the Move fire on May 13, 1985
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| Other names | 3,4-Methylenedioxy-α-ethyl-N-methylbenzylamine; α-Ethyl-N-methylpiperonylamine; 1-Methylamino-1-(3,4-methylenedioxyphenyl)propane |
| Routes of administration | Oral[1] |
| Drug class | Unknown[1] |
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| Duration of action | ~6 hours[1] |
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| Formula | C11H15NO2 |
| Molar mass | 193.246 g·mol−1 |
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M-ALPHA, also known as 3,4-methylenedioxy-α-ethyl-N-methylbenzylamine or as α-ethyl-N-methylpiperonylamine, is a psychoactive drug of the substituted benzylamine group.[1][2] It was reported by Alexander Shulgin in his book PIHKAL as a positional isomer of MDMA.[1][2] Subsequently, the drug was encountered as a designer drug in the United Kingdom in 2010 and was reported to the EMCDDA new drug monitoring service.[3] It was described by Shulgin as similar in action to its demethylated homologue, ALPHA, but with roughly twice the duration and twice the potency.[1] ALPHA itself was described as active at doses of 10 to 140 mg, with a duration of about 3 hours, and producing eyes-closed "dreams", some body tingling, and a pleasant positive feeling, but without any appetite suppression.[1] M-ALPHA was encountered as a designer drug by 2010.[4]
 | This psychoactive drug-related article is a stub. You can help Wikipedia by adding missing information. |
Source: Wikipedia. Article content is retrieved live through the MediaWiki API.
M-ALPHA, also known as 3,4-methylenedioxy-α-ethyl-N-methylbenzylamine or as α-ethyl-N-methylpiperonylamine, is a psychoactive drug of the substituted benzylamine group. It was reported by Alexander Shulgin in his book PIHKAL as a positional isomer of MDMA. Subsequently, the drug was encountered as a designer drug in the United Kingdom in 2010 and was reported to the EMCDDA new drug monitoring service. It was described by Shulgin as similar in action to its demethylated homologue, ALPHA, but with roughly twice the duration and twice the potency. ALPHA itself was described as active at doses of 10 to 140 mg, with a duration of about 3 hours, and producing eyes-closed "dreams", some body tingling, and a pleasant positive feeling, but without any appetite suppression. M-ALPHA was encountered as a designer drug by 2010.
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A and cluster of differentiation molecule 11B (CD11B). The second chain of αMβ2 is the common integrin β2 subunit known as CD18, and integrin αMβ2 thus belongs to the β2 subfamily (or leukocyte) integrins. αMβ2 is expressed on the surface of many leukocytes involved in the innate immune system, including monocytes, granulocytes, macrophages, and natural killer cells and subsets of T and B cells. It mediates inflammation by regulating leukocyte adhesion and migration and has been implicated in several immune processes such as phagocytosis, cell-mediated cytotoxicity, chemotaxis and cellular activation. It is involved in the complement system due to its capacity to bind inactivated complement component 3b (iC3b). The ITGAM (alpha) subunit of integrin αMβ2 is directly involved in causing the adhesion and spreading of cells but cannot mediate cellular migration without the presence of the β2 (CD18) subunit. In genome-wide association studies, single nucleotide polymorphisms in ITGAM had the strongest association with systemic lupus erythematosus, with an odds ratio of 1.65 for the T allele of rs9888739 and lupus. In histopathology, immunohistochemistry with antibodies against CD11B is frequently used to identify macrophages and microglia.
Calcium-activated potassium channel subunit alpha-1 also known as large conductance calcium-activated potassium channel, subfamily M, alpha member 1 (KCa1.1), or BK channel alpha subunit, is a voltage gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes.
In mathematics, the Struve functions Hα(x), are solutions y(x) of the non-homogeneous Bessel's differential equation: x 2 d 2 y d x 2 + x d y d x + ( x 2 − α 2 ) y = 4 ( x 2 ) α + 1 π Γ ( α + 1 2 ) {\displaystyle x^{2}{\frac {d^{2}y}{dx^{2}}}+x{\frac {dy}{dx}}+\left(x^{2}-\alpha ^{2}\right)y={\frac {4\left({\frac {x}{2}}\right)^{\alpha +1}}{{\sqrt {\pi }}\Gamma \left(\alpha +{\frac {1}{2}}\right)}}} introduced by Hermann Struve (1882). The complex number α is the order of the Struve function, and is often an integer. And further defined its second-kind version K α ( x ) {\displaystyle \mathbf {K} _{\alpha }(x)} as K α ( x ) = H α ( x ) − Y α ( x ) {\displaystyle \mathbf {K} _{\alpha }(x)=\mathbf {H} _{\alpha }(x)-Y_{\alpha }(x)} , where Y α ( x ) {\displaystyle Y_{\alpha }(x)} is the Neumann function. The modified Struve functions Lα(x) are equal to −ie−iαπ / 2Hα(ix) and are solutions y(x) of the non-homogeneous Bessel's differential equation: x 2 d 2 y d x 2 + x d y d x − ( x 2 + α 2 ) y = 4 ( x 2 ) α + 1 π Γ ( α + 1 2 ) {\displaystyle x^{2}{\frac {d^{2}y}{dx^{2}}}+x{\frac {dy}{dx}}-\left(x^{2}+\alpha ^{2}\right)y={\frac {4\left({\frac {x}{2}}\right)^{\alpha +1}}{{\sqrt {\pi }}\Gamma \left(\alpha +{\frac {1}{2}}\right)}}} And further defined its second-kind version M α ( x ) {\displaystyle \mathbf {M} _{\alpha }(x)} as M α ( x ) = L α ( x ) − I α ( x ) {\displaystyle \mathbf {M} _{\alpha }(x)=\mathbf {L} _{\alpha }(x)-I_{\alpha }(x)} , where I α ( x ) {\displaystyle I_{\alpha }(x)} is the modified Bessel function of the first kind.
Before the 1921 destruction of Tulsa’s Greenwood District, Black residents had created a remarkable center of business and community life. The district included stores, professional offices, entertainment venues and homes owned by Black citizens. Understanding Greenwood means learning what was built—not only what was burned.
MORE →Brown v. Board of Education in 1954.
